ECG Cath Lab Activation Study

JACC: Cardiovascular Interventions paper

You will review 12-lead index ECGs from consecutive cardiac catheterization-lab activations at three US centers — the same cohort presented at the TCT 2025 late-breaker and published simultaneously in JACC: Cardiovascular Interventions. For each ECG, decide whether you would activate the cath lab, then compare your performance against the reference standard and the AI model.

Herman R, Mumma B, Hoyne J, et al. AI-Enabled ECG Analysis Improves Diagnostic Accuracy and Reduces False STEMI Activations: A Multicenter U.S. Registry. J Am Coll Cardiol Intv. 2026 Jan;19(2):145–156. doi:10.1016/j.jcin.2025.10.018

Reference standard — "true STEMI"

Angiographically confirmed true STEMI was adjudicated from all available clinical data and required:

  • Positive high-sensitivity cardiac troponin — any value above the assay-specific 99th-percentile upper reference limit with a serial rise and/or fall.
  • Angiographic culprit vessel identified by the operator (≥70% stenosis or TIMI flow grade 0 or 1).
  • Also includes MINOCA due to vasospasm, coronary embolization or spontaneous coronary artery dissection.

About the data

  • Your responses, training background and email will be stored securely.
  • Aggregate results may be used in research publications; no personally identifying information will be published without your consent.
  • You may stop at any time. Partial responses will not be used unless you finish and verify your email.
  • Estimated time: 15–25 minutes.

About you

By clicking Begin quiz, you confirm you are a healthcare professional or trainee, and consent to the de-identified (anonymized) use of your ECG interpretations for research purposes as part of the NBI–Queen of Hearts Study.

Case 1 of --  ·  Progress auto-saves
ECG

This patient presents with active, ongoing chest pain. Based on this ECG, would you activate the cath lab?

One last step — verify your email

Click below to send a verification link to your email. Opening that link is required to officially submit your responses and unlock your scorecard — including a detailed case-by-case review of every case where your decision differed from the reference standard.

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